Figure 6
Microcarriers-RPE cells survive in the host striatum and transplantation with RPE cells significantly improve animal behaviours. (A) Low magnification microphotogragh of the striatum with transplants. Arrow indicates the transplants. The scale bar is 0.5 mm. (B) HE staining of the corpus striatum of SD rat injected with microcarriers-RPE (M-RPE). 10 μm sections were stained with hematoxylin-eosin. The scale bar is 20 μm. (C) The corpus striatum of SD rat injected with microcarriers alone as control. Sections were stained as in B. (D) Corpus striatum of SD rat injected with M-RPE was immunostained with cytokeratin antibody. The scale bar is 5 μm. (E) The corpus striatum of SD rat injected with microcarriers only was stained as in D. (F) AIR before transplantation and 4 weeks after transplantation. Data are shown as mean ± S.E.M. *p < 0.05. N = 8.