Figure 5
From: Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors
Blood pharmacokinetics of Gd-dendrimer generations over 600 to 700 minutes. Five to ten voxels were selected from within the common carotid arteries. For the selected voxels, the average blood Gd concentrations were determined for each of the dynamic scan session time points. Shown is the change in average blood Gd concentration of the respective Gd-dendrimer generations over 600 to 700 minutes. A. Gd-G5 (N = 6), B. Gd-G6 (N = 6), C. Gd-G7 (N = 5), D. Gd-G8 (N = 5).