Figure 4

BPA induces modulation of cell cycle regulators and apoptotic players in NB4 cells. (A) Western blot analysis showing p21, p27, p16, cyclin D1 and RB expression levels in NB4 cells treated with 60 μM BPA for 2, 4 and 6 days. (B) Western blot analysis showing TRAIL, FAS, Flip-L and Flip-S expression levels in NB4 cells treated with 60 μM BPA for the indicated days. (C) Western blot analysis showing BCL2 and pBAD expression levels after treated with 60 μM BPA for the indicated days. Total ERKs expression levels account for equal loading.