Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a

Table 7 Comparison of neutrophil expression of CD11b, CD15, CD16, CD18, and CD177 among MPD patients, healthy subjects, and healthy subjects given G-CSF

	Healthy Subjects (n = 43)	All MPD Patients (n = 24)	Polycythemia Vera (n = 11)	Essential Thrombocytosis (n = 13)	G-CSF-Treated Subjects (n = 27)
% Reactive cells
CD11b	55 ± 26	54 ± 28	66 ± 27	44 ± 26†	64 ± 24
CD15	21 ± 25	50 ± 31*†	51 ± 31*†	49 ± 33*†	23 ± 29
CD16	81 ± 22	82 ± 19	83 ± 24	82 ± 16	89 ± 5
CD18	48 ± 33	73 ± 26*	73 ± 30*	73 ± 23*	62 ± 35
CD177	53 ± 23	59 ± 28†	59 ± 29†	58 ± 27†	82 ± 26*
Mean Fluorescence Intensity
CD11b	182 ± 51	187 ± 107	171 ± 100	200 ± 115	155 ± 67
CD15	480 ± 284	374 ± 236	373 ± 265	377 ± 221	441 ± 443
CD16	2,946 ± 1,345	2,580 ± 1,138†	2,410 ± 1,430†	2,725 ± 853†	890 ± 336*
CD18	451 ± 300	250 ± 81*	267 ± 100	237 ± 61*	253 ± 107*
CD177	625 ± 383	575 ± 267†	587 ± 251†	566 ± 290†	2,012 ± 1088*

ISSN: 1479-5876