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Table 7 Comparison of neutrophil expression of CD11b, CD15, CD16, CD18, and CD177 among MPD patients, healthy subjects, and healthy subjects given G-CSF

From: Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a

  Healthy Subjects
(n = 43)
All MPD Patients
(n = 24)
Polycythemia Vera
(n = 11)
Essential Thrombocytosis
(n = 13)
G-CSF-Treated Subjects
(n = 27)
% Reactive cells
CD11b 55 ± 26 54 ± 28 66 ± 27 44 ± 26† 64 ± 24
CD15 21 ± 25 50 ± 31*† 51 ± 31*† 49 ± 33*† 23 ± 29
CD16 81 ± 22 82 ± 19 83 ± 24 82 ± 16 89 ± 5
CD18 48 ± 33 73 ± 26* 73 ± 30* 73 ± 23* 62 ± 35
CD177 53 ± 23 59 ± 28† 59 ± 29† 58 ± 27† 82 ± 26*
Mean Fluorescence Intensity
CD11b 182 ± 51 187 ± 107 171 ± 100 200 ± 115 155 ± 67
CD15 480 ± 284 374 ± 236 373 ± 265 377 ± 221 441 ± 443
CD16 2,946 ± 1,345 2,580 ± 1,138† 2,410 ± 1,430† 2,725 ± 853† 890 ± 336*
CD18 451 ± 300 250 ± 81* 267 ± 100 237 ± 61* 253 ± 107*
CD177 625 ± 383 575 ± 267† 587 ± 251† 566 ± 290† 2,012 ± 1088*
  1. * p < 0.05 compared to healthy subjects
  2. † p < 0.05 compared to subjects given G-CSF
  3. Fluor = fluorescence