Table 3 Genes up-regulated the most in MPD neutrophils compared to those from healthy subjects (p < 0.05, tests)
Gene | Â | Fold increase | p |
|---|---|---|---|
Rg9mtd1 | PREDICTED: RNA (guanine-9-) methyltransferase domain containing 1 (Rg9mtd1) | 4.79 | 0.00844 |
HPR | haptoglobin-related protein (HPR) | 4.55 | 0.000443 |
ZDHHC19 | zinc finger, DHHC-type containing 19 (ZDHHC19) | 4.34 | 0.00278 |
ZNF652 | zinc finger protein 652 (ZNF652) | 3.90 | 5.90E-05 |
ADCY3 | adenylate cyclase 3 (ADCY3) | 3.64 | 0.0121 |
PROK2 | Prokineticin 2 | 3.60 | 0.000166 |
C19orf59 | chromosome 19 open reading frame 59 (C19orf59) | 3.33 | 0.0139 |
ZFYVE21 | zinc finger, FYVE domain containing 21 (ZFYVE21) | 3.32 | 0.00362 |
CCR1 | chemokine (C-C motif) receptor 1 (CCR1) | 3.14 | 0.000335 |
EGR1 | early growth response 1 (EGR1) | 3.13 | 0.0229 |
ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 (ST3GAL4) | 3.13 | 0.00225 |
PADI2 | peptidyl arginine deiminase, type II (PADI2) | 3.12 | 2.90E-06 |
AXUD1 | AXIN1 up-regulated 1 (AXUD1) | 3.08 | 0.00546 |
LOC728488 | PREDICTED: similar to Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145) (LOC728488) | 3.06 | 0.00241 |
| Â | Transcribed locus, moderately similar to XP_001235777.1 PREDICTED: hypothetical protein [Gallus gallus] | 3.04 | 0.0123 |
CBS | cystathionine-beta-synthase (CBS) | 2.97 | 0.00183 |
| Â | CDNA: FLJ21549 fis, clone COL06253 | 2.96 | 0.00649 |
ACRV1 | acrosomal vesicle protein 1 (ACRV1), transcript variant 11. | 2.91 | 0.00574 |
UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 2.84 | 0.0179 |
GYG1 | glycogenin 1 (GYG1) | 2.75 | 0.0146 |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant c | 2.73 | 0.00792 |
LMO4 | LIM domain only 4 (LMO4) | 2.69 | 0.000128 |
MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) (MCL1), transcript variant 1 | 2.67 | 0.000287 |
LOC729915 | PREDICTED: similar to Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145) (LOC729915) | 2.57 | 0.0172 |
GALNT14 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) | 2.57 | 0.00853 |
FAM69A | family with sequence similarity 69, member A (FAM69A) | 2.57 | 0.0446 |
MED26 | Mediator complex subunit 26 | 2.56 | 0.0109 |
C1orf115 | chromosome 1 open reading frame 115 (C1orf115) | 2.55 | 0.0309 |
KIFC3 | kinesin family member C3 (KIFC3) | 2.54 | 0.00290 |
Rg9mtd1 | Transcribed locus | 2.53 | 0.0113 |