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Table 3 Genes up-regulated the most in MPD neutrophils compared to those from healthy subjects (p < 0.05, tests)

From: Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a

Gene   Fold increase p
Rg9mtd1 PREDICTED: RNA (guanine-9-) methyltransferase domain containing 1 (Rg9mtd1) 4.79 0.00844
HPR haptoglobin-related protein (HPR) 4.55 0.000443
ZDHHC19 zinc finger, DHHC-type containing 19 (ZDHHC19) 4.34 0.00278
ZNF652 zinc finger protein 652 (ZNF652) 3.90 5.90E-05
ADCY3 adenylate cyclase 3 (ADCY3) 3.64 0.0121
PROK2 Prokineticin 2 3.60 0.000166
C19orf59 chromosome 19 open reading frame 59 (C19orf59) 3.33 0.0139
ZFYVE21 zinc finger, FYVE domain containing 21 (ZFYVE21) 3.32 0.00362
CCR1 chemokine (C-C motif) receptor 1 (CCR1) 3.14 0.000335
EGR1 early growth response 1 (EGR1) 3.13 0.0229
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 (ST3GAL4) 3.13 0.00225
PADI2 peptidyl arginine deiminase, type II (PADI2) 3.12 2.90E-06
AXUD1 AXIN1 up-regulated 1 (AXUD1) 3.08 0.00546
LOC728488 PREDICTED: similar to Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145) (LOC728488) 3.06 0.00241
  Transcribed locus, moderately similar to XP_001235777.1 PREDICTED: hypothetical protein [Gallus gallus] 3.04 0.0123
CBS cystathionine-beta-synthase (CBS) 2.97 0.00183
  CDNA: FLJ21549 fis, clone COL06253 2.96 0.00649
ACRV1 acrosomal vesicle protein 1 (ACRV1), transcript variant 11. 2.91 0.00574
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 2.84 0.0179
GYG1 glycogenin 1 (GYG1) 2.75 0.0146
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant c 2.73 0.00792
LMO4 LIM domain only 4 (LMO4) 2.69 0.000128
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) (MCL1), transcript variant 1 2.67 0.000287
LOC729915 PREDICTED: similar to Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145) (LOC729915) 2.57 0.0172
GALNT14 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14) (GALNT14) 2.57 0.00853
FAM69A family with sequence similarity 69, member A (FAM69A) 2.57 0.0446
MED26 Mediator complex subunit 26 2.56 0.0109
C1orf115 chromosome 1 open reading frame 115 (C1orf115) 2.55 0.0309
KIFC3 kinesin family member C3 (KIFC3) 2.54 0.00290
Rg9mtd1 Transcribed locus 2.53 0.0113