Figure 2

Gene expression profiling of differentially expressed MPD neutrophil genes. The 1,006 genes differentially expressed among 6 MPD patients, 5 healthy subjects and 6 subjects given 5 days of G-CSF (F-test, p < 0.005) were analyzed by hierarchical clustering of Eisen. Genes in cluster 1 were up-regulated only in MPD neutrophils and those in cluster 2 were down-regulated only in MPD neutrophils. The purple bar indicates neutrophils from patients with MPDs and the yellow bar those from healthy subjects and the blue bar from healthy subjects given G-CSF.