Figure 1

Gene expression analysis of MPD neutrophils. Gene expression of neutrophils from 6 MPD patients, 5 healthy subject neutrophils and 6 healthy subjects given G-CSF was analyzed using a microarray with more than 35,000 probes. The 3,617 genes that were expressed in at least 80% of samples and were up-regulated at least two-fold in one sample were analyzed by unsupervised hierarchical clustering of Eisen. The purple bar indicates neutrophils from patients with MPDs and the yellow bar those from healthy subjects and the blue bar from healthy subjects given G-CSF.