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Table 4 Comparison of Cut-off Values, Sensitivity, and Specificity between serum CEA and HMGB1 levels for the screening of high-risk group (IM and adenoma)

From: Serum high mobility group box-1 (HMGB1) is closely associated with the clinical and pathologic features of gastric cancer

  CEA (ng/ml) HMGB1 (ng/ml)
Cut-off value (ng/ml) 2.5 2 4.5 4
Sensitivity (%) 39 49 66 70
Specificity (%) 76 62 72 64