Progesterone receptor does not improve the performance and test effectiveness of the conventional 3-marker panel, consisting of estrogen receptor, vimentin and carcinoembryonic antigen in distinguishing between primary endocervical and endometrial adenocarcinomas in a tissue microarray extension study

Table 4 Panel performance for the diagnosis of EMA (sample size 24)

	ER > 3	Vim > 3	CEA > 3	PR > 3	number	% with this panel
	-	-	-	-	2	8.33%
	-	-	+	-	1	4.17%
	-	+	-	-	3	12.50%
	+	-	-	-	2	8.33%
	+	-	-	+	2	8.33%
	+	-	+	+	1	4.17%
*	+	+	-	-	2	*8.33%*
*	+	+	-	+	9	*37.50%*
	+	+	+	+	2	8.33%

1. -: score negative, +: score positive
2. Despite PR, panel expressions with ER+/Vim+/CEA- in mark-* were defined as typical EM-type immunoprofiles. Others were defined as non-typical EM-type immunoprofiles.
3. 11 cases with typical EM-type (*) immunoprofile expression also exhibited PR (+) in 9 cases, and PR (-) in 2 cases.

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