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Figure 3 | Journal of Translational Medicine

Figure 3

From: Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma

Figure 3

The sigma-2 ligand SV119 induces moderate apoptosis in both G0 and G1 to G2/S phase of pancreatic cancer cells in vitro. The murine pancreatic adenocarcinoma cell, Panc02, was treated with SV119 alone or in combination with gemcitabine or paclitaxel. After 24 hours of treatment, samples were stained for cleaved caspase-3 and Ki67. Representative histograms are shown from an experiment performed in triplicate.

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