Table 2 Estimated Characteristics of Three Testing Methodologies for Norovirus, Based On Latent Class Analysis and Composite Reference Standard.
Sensitivity (95% CI) | Specificity (95% CI) | Positive Predictive Value (95% CI) | Negative Predictive Value (95% CI) | |
|---|---|---|---|---|
Latent Class Model, prevalence (95% CI) = 0.42 (0.35, 0.49) | ||||
RT 2 -PCR | 100% (100%, 100%) | 86% (76%, 95%) | 88% (74%, 93%) | 100% (100%, 100%) |
EIA | 86% (75%, 95%) | 93% (85%, 99%) | 92% (80, 98%) | 87% (83%, 96%) |
EM | 18% (8%, 30%) | 100% (100%, 100%) | 100% (100%, 100%) | 63% (55%, 70%) |
Composite Reference Standard, prevalence (95% CI) = 0.37 (0.26, 0.49) | ||||
RT 2 -PCR | 100% (100%, 100%) | 78% (66%, 88%) | 82% (57%, 86%) | 100% (100%, 100%) |
EIA | 97% (91%, 100%) | 96% (90%, 100%) | 96% (83%, 100%) | 97% (94%, 100%) |
EM | 20% (9%, 33%) | 100% (100%, 100%) | 100% (100%, 100%) | 68% (56%, 79%) |