Skip to main content

Table 3 Apoptosis induction in HepG2 cell variants by 48 h treatment with DMSO or 20–300 μM RES

From: Caveolin-1 enhances resveratrol-mediated cytotoxicity and transport in a hepatocellular carcinoma model

  Percent Apoptosis (%)
Cell groups   Res (μM)
  DMSO 20 50 100 200 300
HepG2 1.53 ± 1.6 6.83 ± 1.9 10.93 ± 1.5 31.2 ± 2.1 63.2 ± 0.8 80.6 ± 1.9
CAV1 3.62 ± 1.8 13.2 ± 1.0 17.91 ± 2.5* 78.7 ± 1.7* 93.6 ± 2.0* 97.1 ± 1.7*
CAVM1 2.19 ± 1.8 9.62 ± 1.1 13.5 ± 1.8 23.1 ± 0.9 74.1 ± 1.8* 90.3 ± 0.6*
CAVM2 3.08 ± 1.3 11.5 ± 1.4 15.3 ± 1.6 50.1 ± 1.7* 83.4 ± 1.5* 93.5 ± 2.4*
CAVRNAi 1.37 ± 1.7 5.05 ± 1.4 9.78 ± 1.1 24.8 ± 2.5 57.7 ± 2.4 75.4 ± 3.1
GFP 1.44 ± 1.1 6.05 ± 1.8 11.2 ± 2.0 32.7 ± 1.6 65.4 ± 2.1 82.3 ± 3.0
  1. *P < 0.05 vs control, ( ± SD, n = 3)