Figure 8From: Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCsRepresentative flowcytometry plots (class I ± II pulsed DCT). Tetramer+CD8+T cell responses (in patient L003) elicited from vaccinating with the class I (p865) epitope alone compared with the class I (p540)+ class II epitopes (p766 and p672), through vaccination time points V0–V4 (V0: baseline, V4: following 4th vaccination). The arrow highlights the enhanced response at V4 compared with V0. CD8+T cell tetramer+ response to an irrelevant HLA*A201 MAGE antigen, not used in the vaccination, was measured as a negative control; 150,000 events were acquired and analysed.Back to article page