Figure 4

Tetramer+ CD8+ T cell responses (mean +/- SD) to only class I hTERT pulsed DCs. Vaccinations with DCT and DCTI in 10 patients. Both vaccines (DCT and DCTI) were equivalent in eliciting CD8+T cell responses and there were no statistically significant differences between DCT and DCTI at any vaccination time point (NS-not significant, p = 0.45, t-test). CD8+T cell tetramer+ response to an irrelevant HLA*A201 MAGE antigen, not used in the vaccination, was measured as a negative control; 150,000 events were acquired and analysed.