Skip to main content

Table 1 Proximity ligation assay reveals 11 tumor markers that are significantly elevated in pancreatic cancer cases compared to healthy controls.

From: Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis

Tumor Marker

p* <

Fold Difference†

Lower 95% CI

Upper 95% CI

OPN

1.20 × 10-12

2.04

14.99

15.38

CA19-9

6.82 × 10-12

16.41

17.57

18.55

CHI3L1

8.60 × 10-8

3.13

18.42

19.06

CA125

4.86 × 10-7

3.54

20.20

20.89

CEA

1.35 × 10-5

3

17.70

18.35

VEGF

3.22 × 10-4

2.17

14.04

14.65

MESO

0.0014

1.39

20.63

20.92

IGF2

0.0022

1.35

21.45

21.78

IL-7

0.01

1.83

15.88

16.41

MIF

0.01

1.58

16.35

16.88

ERBB2

0.02

1.18

18.57

18.84

EpCam

0.04

0.63

12.85

13.35

EGFR

0.07

0.89

16.58

16.85

IL-1

0.28

1.36

16.72

17.18

ADAM8

0.29

1.35

7.41

7.85

Galectin

0.3

0.94

10.34

10.54

CTGF

0.4

1.12

11.07

11.60

CPA1

0.46

1.07

12.06

12.38

TNF

0.49

1.22

13.03

13.44

SLPI

0.68

1.08

20.41

20.73

CA15-3

0.82

1.02

16.88

17.24

  1. * - p-values calculated using Welch-Satterthwaite Student's t-test and a two-sided distribution
  2. † - Fold differences calculated comparing cases to controls using log2 medians in PLA units