Figure 3
(A) Correlation of frequency and amplitude of tremor in 22 ET patients. Each data point represents one patient. A negative correlation was noted between the frequency and amplitude in 22 ET patients. Also note the frequency of ET ranges from 3–11 Hz in the patients. G = 0.0098 m/s2. (B) The frequency of the oscillations is determined primarily by Ih and IT, which in turn depend upon the distribution of ion channel subtypes (upper panels). The frequency of oscillation is predominantly determined by Ih, while its amplitude is predominantly determined by IT. Notice in panel 'B' that as we increase IT the red color appears sooner for higher values of Ih but is not present when Ih is relatively low (~2 ms). (C) The amplitude of tremor is predominantly determined by the value of IT.