Table 4 Toxicity of docetaxel and gemcitabine combinations per patient
Arm A n = 39 | Arm B n = 38 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toxicity grade | 2 | 3 | 4 | 2 | 3 | 4 | ||||||
Hematological | n | (%) | N | (%) | n | (%) | n | (%) | n | (%) | n | (%) |
Leukopenia | 6 | (15) | 9 | (23) | 4 | (10) | 3 | (8) | 2 | (5) | 2 | (5) |
Anemia | 12 | (31) | 1 | (3) | 0 | - | 5 | (13) | 0 | - | 0 | - |
Thrombocytopenia | 1 | (3) | 2 | (5) | 0 | - | 2 | (5) | 0 | - | 0 | - |
Neutropenia | 3 | (8) | 7 | (18) | 14* | (36) | 6 | (16) | 4 | (11) | 7† | (8) |
Non hematological | ||||||||||||
Hepatotoxicity | 4 | (10) | 3 | (8) | 0 | - | 5 | (13) | 3 | (8) | 1 | (3) |
Mucositis | 5 | (13) | 3 | (8) | 0 | - | 2 | (5) | 0 | - | 0 | - |
Nausea | 3 | (8) | 3 | (8) | 0 | - | 3 | (8) | 2 | (5) | 0 | - |
Vomiting | 3 | (8) | 2 | (5) | 0 | 2 | (5) | 2 | (5) | 0 | - | |
Diarrhea | 7 | (18) | 3 | (8) | 1 | (3) | 5 | (13) | 0 | - | 0 | - |
Asthenia | 8 | (21) | 2 | (5) | 0 | - | 1 | (3) | 2 | (5) | 0 | - |
Alopecia | 4 | (10) | 2 | (5) | 0 | - | 0 | - | 3 | (8) | 0 | - |
Skin | 5 | (13) | 0 | - | 0 | - | 2 | (5) | 0 | - | 0 | - |
Other | 8 | (21) | 3 | (8) | 1§3) | (3) | 8 | (21) | 0 | - | 2‡ | (5) |