Table 1 TCR α/β Complementarity Determining Region Residues Identified from gp100_154–162 specific CD8+ T cell clones

Patient 2

12.1

N

S

A

S

Q

S

V

Y

S

S

G

V

V

N

M

N

S

N

Y

Q

L

I

Patient 5

8.1

Y

G

G

T

V

N

Y

F

S

G

D

P

L

A

V

N

G

D

D

K

I

I

Patient 6

5

D

S

S

S

T

Y

I

F

S

N

M

D

A

E

M

A

N

S

G

Y

A

L

N

Patient 7

5

D

S

S

S

T

Y

I

F

S

N

M

D

A

E

N

P

E

G

N

D

M

R

TRBV

Patient 2

15

L

N

H

N

V

Y

Y

D

K

D

F

A

T

S

Q

E

A

S

F

T

D

T

Q

Y

Patient 5

7.6

S

G

H

V

S

F

N

Y

E

A

Q

A

S

S

L

G

G

G

Q

D

T

Q

Y

Patient 6

12.3

S

G

H

N

S

F

N

N

N

V

P

A

S

S

P

G

G

G

E

Q

F

Patient 7

11.2

S

G

H

A

T

F

Q

N

N

G

V

A

S

S

P

G

G

G

G

E

Q

F