Figure 1From: Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cellsLXRs are expressed in peripheral blood cells. (A) RNA from peripheral blood mononuclear cells obtained from normal human donors was assayed for LXRα and LXRβ transcript levels using qPCR. Expression values were normalized to GAPDH levels, represented as the mean +/- SEM. (B) LXRα protein levels in protein extracts from PBMCs from these same donors were detected by Western blotting using rabbit anti-human LXRα polyclonal antisera.Back to article page