Figure 5From: Protective CD8+ T-cell responses to cytomegalovirus driven by rAAV/GFP/IE1 loading of dendritic cellsCytotoxicity assay. AAV/GFP/IE1 vectors for DC loading and multiple targets generated using various vectors. Targets were generated by IE1 positive and negative vector loading into PBMC. Resulting CTL killing is shown. IE1 negative PBMCs (no Ag) and K562 cells were not killed, indicating strong antigen specificity for the CTLs generated by AAV/IE1 loading.Back to article page