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Table 3 Biochemical parameters, biological processes and pathways that distinguish Prakriti types in females

From: Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda

Distinguishing Parameters (Females)

Vata

Pitta

Kapha

Biochemical

 

Basophils

NS

+

-

 

Micronutrients

Zinc

NS

+

-

  

Copper

-

+

NS

  

Phosphorus

-

+

-

Biological Processes

Transport

protein import into nucleus

+

-

-

  

NLS-bearing substrate import into nucleus

+

-

-

Biological Pathways

Immune system

Toll-like receptor signaling pathway

-

+

-

 

Cellular process

Apoptosis

-

+

-

  

Regulation of actin cytoskeleton

-

-

+

 

Environmental Information processing

MAPK signaling pathway

-

-

+

  

Jak-STAT signaling pathway

-

+

+

  

Cytokine-cytokine receptor interaction

-

+

+

 

Sensory system

Olfactory transduction

+

-

+

 

Diseases

Epithelial cell signaling in Helicobacter pylori infection

-

+

-

  

Neurodegenerative disorders

-

-

+

  

Dentatorubropallidoluysian atrophy (DRPLA)

+

+

-

  1. Significantly different biochemical parameters (p ≤ 0.05), enriched biological processes (P ≤ 0.05, Bonferroni corrected) and pathways (p ≤ 0.05) in different Prakriti groups in males (A) and females (B). The biological processes were analysed using GO tools and pathway analysis was carried out using Pathway Express of ONTOTOOLs. (+) and (-) indicate high and low levels respectively. NS – non significant.