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Table 2 Apoptotic cells (%) in LNCaP line by TUNEL assay

From: Zoledronic acid increases docetaxel cytotoxicity through pMEK and Mcl-1 inhibition in a hormone-sensitive prostate carcinoma cell line

  

Observation time

  

72 h

96 h

120 h

Control

 

1.5

2.0

2.0

Doc 1 h

0.001 μM

1.3

1.1

4.8

 

0.01 μM

2.5

3.8

9.2

Zol continuous

exposure

100 μM

4.9

11.5

37.8*

Doc (0.001 μM) +

Zol (100 μ M) 1 h → Zol (100 μM)

11.2

20.1

30.8*

Doc (0.01 μM) +

Zol (100 μ M) 1 h → Zol (100 μM)

40.2

41.6

66.5*

  1. *Significance at p < 0.05 by t test