bFGF levels vs. paclitaxel effects (IC
) in tumor subgroups. (A) complete data set (n = 87), (B) tumors with negative aFGF staining (n = 44), (C) tumors with positive aFGF staining (n = 43), (D) tumors with negative p53 staining (n = 54), (E) tumors with positive p53 staining (n = 33), (F) low stage tumors (stage I or II, n = 39), (G) high stage tumors (stage III or IV, n = 48), (H) tumors with bFGF levels less than or equal to the median value of 9.8 pg/mg (n = 44), and (I) tumors with bFGF levels greater than the median value (n = 43). Note the different x-axis in panel H (ranged from 0 to 10 pg/mg protein) compared to all other panels (ranged from 0 to 200 pg/mg protein). The r2 and p values for the correlations within each group are provided. The differences between the r2 values between each pair of subgroups (e.g., B vs C, D vs E, F vs G, H vs I) were significant (p < 0.05). The differences between the r2 values between the four subgroups with the high r2 values (i.e., negative aFGF, high stage, positive p53 staining, higher-than-median bFGF levels) and all 87 tumors were also significant (p < 0.05).