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Table 4 Genes differentially expressed between hematopoietic stem cells (HSCs) and peripheral blood leukocytes (PBLs)

From: Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis

Expression Increased in HSCs

Expression Increased in PBLs

Gene Symbol

Description

Fold Change

Gene Symbol

Description

Fold Change

GATA2

GATA-binding protein 2

237.82

CARD14

Caspase recruitment domain protein 14

25.59

MYCN

N-myc

97.75

LTBR

Lymphotoxin-Beta receptor precursor = Tumor necrosis factor receptor 2 related protein = Tumor necrosis factor C receptor

18.83

CRHBP

CRF-BP = corticotropin-releasing factor binding protein

65.52

GPR65

TDAG8 = putative G protein-coupled receptor induced during activation-induced apoptosis of T cells = G protein-coupled receptor 65

18.33

FHL1

Four and a half LIM domains 1

58.2

FCGR3A

CD16 = Fcgamma receptor IIIa

18.15

ERG

V-ets erythroblastosis virus E26 oncogene homolog (avian)

43.57

ITGAM

Integrin, alpha M (complement component 3 receptor 3 subunit)

16.96

NPR3

Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

42.04

SGSH

N-sulfoglucosamine sulfohydrolase (sulfamidase)

16.64

SCHIP1

Schwannomin interacting protein 1

41.77

ITGB7

Integrin, beta 7

16.39

MSRB3

Methionine sulfoxide reductase B3

35.29

GNLY

Granulysin

15.21

MYB

V-myb myeloblastosis viral oncogene homolog (avian)

32.99

ALOX5AP

Arachidonate 5-lipoxygenase-activating protein

15.11

DEPDC6

DEP domain containing 6

28.85

CD48

CD48 = BLAST-1

14.81

EPDR1

Ependymin related protein 1 (zebrafish)

27.88

IL10RA

Interleukin 10 receptor, alpha

13.71

TRH

Thyrotropin-releasing hormone

26.63

CX3CR1

Chemokine (C-X3-C motif) receptor 1

13.64

NGFRAP1

Nerve growth factor receptor (TNFRSF16) associated protein 1

25.86

COTL1

Coactosin-like 1 (Dictyostelium)

13.4

SERPING1

Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)

25.83

ADAM19

ADAM metallopeptidase domain 19 (meltrin beta)

13.24

MAP7

Microtubule-associated protein 7

25.11

IL2RB

IL-2 receptor beta chain

13

SOCS2

Suppressor of cytokine signaling 2

24.44

ITK

IL2-inducible T-cell kinase

11.91

TSC22D1

TSC22 domain family, member 1

24.12

KLRC4

Killer cell lectin-like receptor subfamily C, member 4

11.36

H1F0

H1 histone family, member 0

22.71

CCL4

MIP-1 beta

11.22

RBPMS

RNA binding protein with multiple splicing

22.67

CTSH

Cathepsin H

11.18

CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

22.64

EBI2

Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)

10.69

CDCA7

Cell division cycle associated 7

22.49

GIMAP4

GTPase, IMAP family member 4

10.28

CYTL1

Cytokine-like 1

20.9

POU2F2

POU domain, class 2, transcription factor 2

10.22

FLT3

Fms-related tyrosine kinase 3

20.45

CXCR4

CXCR4 = CXC chemokine receptor 4

10.11

PRKAR2B

Protein kinase, cAMP-dependent, regulatory, type II, beta

20.09

CYP4A11

Cytochrome P450, family 4, subfamily A, polypeptide 11

10.1

TRIM58

Tripartite motif-containing 58

19.18

LGALS3

Lectin, galactoside-binding, soluble, 3 (galectin 3)

9.61

FSCN1

Fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

18.91

SNX27

Sorting nexin family member 27

9.44

C1orf150

Chromosome 1 open reading frame 150

18.83

TRIM26

Tripartite motif-containing 26

9.23

TRH

Thyrotropin-releasing hormone

17.56

SNX27

Sorting nexin family member 27

9.05

KIT

V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

17.27

CSPG2

Chondroitin sulfate proteoglycan 2 (versican)

8.89

WASF1

WAS protein family, member 1

16.75

IL32

Interleukin 32

8.76

  1. *The groups were compared using t-tests (p < 0.001).