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Table 4 Genes differentially expressed between hematopoietic stem cells (HSCs) and peripheral blood leukocytes (PBLs)

From: Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis

Expression Increased in HSCs Expression Increased in PBLs
Gene Symbol Description Fold Change Gene Symbol Description Fold Change
GATA2 GATA-binding protein 2 237.82 CARD14 Caspase recruitment domain protein 14 25.59
MYCN N-myc 97.75 LTBR Lymphotoxin-Beta receptor precursor = Tumor necrosis factor receptor 2 related protein = Tumor necrosis factor C receptor 18.83
CRHBP CRF-BP = corticotropin-releasing factor binding protein 65.52 GPR65 TDAG8 = putative G protein-coupled receptor induced during activation-induced apoptosis of T cells = G protein-coupled receptor 65 18.33
FHL1 Four and a half LIM domains 1 58.2 FCGR3A CD16 = Fcgamma receptor IIIa 18.15
ERG V-ets erythroblastosis virus E26 oncogene homolog (avian) 43.57 ITGAM Integrin, alpha M (complement component 3 receptor 3 subunit) 16.96
NPR3 Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 42.04 SGSH N-sulfoglucosamine sulfohydrolase (sulfamidase) 16.64
SCHIP1 Schwannomin interacting protein 1 41.77 ITGB7 Integrin, beta 7 16.39
MSRB3 Methionine sulfoxide reductase B3 35.29 GNLY Granulysin 15.21
MYB V-myb myeloblastosis viral oncogene homolog (avian) 32.99 ALOX5AP Arachidonate 5-lipoxygenase-activating protein 15.11
DEPDC6 DEP domain containing 6 28.85 CD48 CD48 = BLAST-1 14.81
EPDR1 Ependymin related protein 1 (zebrafish) 27.88 IL10RA Interleukin 10 receptor, alpha 13.71
TRH Thyrotropin-releasing hormone 26.63 CX3CR1 Chemokine (C-X3-C motif) receptor 1 13.64
NGFRAP1 Nerve growth factor receptor (TNFRSF16) associated protein 1 25.86 COTL1 Coactosin-like 1 (Dictyostelium) 13.4
SERPING1 Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) 25.83 ADAM19 ADAM metallopeptidase domain 19 (meltrin beta) 13.24
MAP7 Microtubule-associated protein 7 25.11 IL2RB IL-2 receptor beta chain 13
SOCS2 Suppressor of cytokine signaling 2 24.44 ITK IL2-inducible T-cell kinase 11.91
TSC22D1 TSC22 domain family, member 1 24.12 KLRC4 Killer cell lectin-like receptor subfamily C, member 4 11.36
H1F0 H1 histone family, member 0 22.71 CCL4 MIP-1 beta 11.22
RBPMS RNA binding protein with multiple splicing 22.67 CTSH Cathepsin H 11.18
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 22.64 EBI2 Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) 10.69
CDCA7 Cell division cycle associated 7 22.49 GIMAP4 GTPase, IMAP family member 4 10.28
CYTL1 Cytokine-like 1 20.9 POU2F2 POU domain, class 2, transcription factor 2 10.22
FLT3 Fms-related tyrosine kinase 3 20.45 CXCR4 CXCR4 = CXC chemokine receptor 4 10.11
PRKAR2B Protein kinase, cAMP-dependent, regulatory, type II, beta 20.09 CYP4A11 Cytochrome P450, family 4, subfamily A, polypeptide 11 10.1
TRIM58 Tripartite motif-containing 58 19.18 LGALS3 Lectin, galactoside-binding, soluble, 3 (galectin 3) 9.61
FSCN1 Fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) 18.91 SNX27 Sorting nexin family member 27 9.44
C1orf150 Chromosome 1 open reading frame 150 18.83 TRIM26 Tripartite motif-containing 26 9.23
TRH Thyrotropin-releasing hormone 17.56 SNX27 Sorting nexin family member 27 9.05
KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 17.27 CSPG2 Chondroitin sulfate proteoglycan 2 (versican) 8.89
WASF1 WAS protein family, member 1 16.75 IL32 Interleukin 32 8.76
  1. *The groups were compared using t-tests (p < 0.001).