Skip to main content

Table 2 Serum biochemical analyses in four GRMD dogs under hIDPSC therapy (MT1, MT2, FT1 and FT2) and matched age control (MC and FC).

From: Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic?

ANIMALS 30 days

CK (U/L)

ALT (U/L)

FA (U/L)

Urea (mg/dL)

Creat (mg/dL)

RBC (mlh/mm3)

Ht (%)

Hb (g/dL)

WBC (mil/mm3)

Reference values*

0–200

until 50

until 130

until 40

until 1.5 – 2

3.5 – 6

26 – 39

8.5 – 13

8,5 – 17,3

FC

9,275

162

500

31

1

3.3

27

7.1

19,300

FT1-S

9,274

159

478

28.6

1

3.6

25

7.6

26,300

FT2-IM

4,647

134

352

22

0.98

4

26

8.8

32,000

MC

3,618

110

260

32.8

1

4.2

30

8.8

32,300

MT1-S

7,716

230

174

30

1

4.6

34

11

24,800

MT2- IM

5,668

163

217

32.9

1.1

4.7

33

11.5

23,600

ANIMALS 75 days

CK (U/L)

ALT (U/L)

FA (U/L)

Urea (mg/dL)

Creat (mg/dL)

RBC (mlh/mm 3 )

Ht (%)

Hb (g/dL)

WBC (mil/mm 3 )

FC

32,599

294

300

46

0.85

4.8

29

9.2

28,200

FT1-S

15,100

245

161

43.5

0.92

4.3

26

8.7

34,800

FT2-IM

24,784

192

117

37.8

0.9

4.6

28

9.2

30,200

MC

15,257

189

138

37.8

0.9

4.1

27

8.9

36,600

MT1-S

30,729

293

181

42.8

0.94

4.6

29

9.9

25,900

MT2- IM

15,291

237

191

46.9

0.92

4.6

28

9.7

39,100

ANIMALS 180 days

CK (U/L)

ALT (U/L)

FA (U/L)

Urea (mg/dL)

Creat (mg/dL)

RBC (mlh/mm 3 )

Ht (%)

Hb (g/dL)

WBC (mil/mm 3 )

Reference values*

0–200

until 50

until 130

until 40

until 1.5 – 2

5.5 – 7

34 – 40

11 – 15.5

8 – 16,000

FC

56,736

416

58

40

0.4

5.5

39

12.4

16,200

FT1-S

48,960

396

28

23

0.5

5.4

38

12.1

15,500

FT2-IM

51,296

228

8

38

0.4

6.0

39

13.1

14,100

MC

56,736

524

91

51

0.5

5.6

37

12

20,400

MT1-S

25,632

440

66

55

0.4

5.5

36

12.5

18,600

MT2- IM

36,512

500

62

40

0.4

5.5

38

12

15,600

ANIMALS 360 days

CK (U/L)

ALT (U/L)

FA (U/L)

Urea (mg/dL)

Creat (mg/dL)

RBC (mlh/mm 3 )

Ht (%)

Hb (g/dL)

WBC (mil/mm 3 )

reference values*

0–200

until 50

until 130

until 40

until 1.5 – 2

5 – 8

37 – 54

12 – 18

6 – 15,000

FC**

         

FT1-S **

         

FT2-IM

35,712

764

8

35

0.4

6.1

41

13.1

14,000

MC

41,920

376

49

48

0.6

5.6

36

13

20,000

MT1-S

40,384

604

41

34

0.5

5.2

33

12

18,000

MT2- IM***

9,280

208

33

50

0.7

5.1

34

11.7

15,000

GRMD Control Data (n:6)

35,710

551

43.25

35.75

0.52

5.75

37.75

12.87

14,6

Normal Dogs Data (n: 6)

145

15

82

28

1.8

4.2

30.7

14.2

11,7

  1. Also, control dogs were used from all colony animals (Normal X Affected)
  2. *Reference values from Veterinary Hospital (HOVET) – FMVZ-USP and FMVZ-UNESP, São Paulo, Brazil.
  3. ** Animal died with 10 months (FC) and 8 months (FT1-S) *** Animal died with 13 months
Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us