Early transplantation of human immature dental pulp stem cells from baby teeth to golden retriever muscular dystrophy (GRMD) dogs: Local or systemic?

Table 1 GRMD dogs, born April, 2006 used for IDPSC transplantation and respective controls.

Dog n°	Dog name	Cell Treatment	Onset treatment	Biopsy after 1^a injection	Progression/motility	Physical score		Outcome of experiment at time ...
						180d	365d
♀	Laka 2L5	Control	-	0 d	Severe/major decline	4	†	Died (300d)
FC				107 d				Ascite
♀	Lancy 2L6	hlDPSC – S	Just with	107 d	Severe/major decline	3	†	Died (240d)
FT1-S			28 d					Ascite
♀	Amandita 2L4	hlDPSC – IM	Just with	107 d	Mild/modest decline	4	†	Died (480d)
FT2-IM			28 d					Cardiac failure
♂	Bis 2L2	Control	-	117 d	Severe/major decline	2	17	Alive
MC
♂	Chokito 2L3	hlDPSC – S	Start with 44 d	47 d	Mild/modest decline	5	11	Alive and well
MT1-S
			Followed by 8 injections/month	117 d
				365 d
♂	Toddy 2L7	hlDPSC – IM	Start with 44 d	47 d	Severe/major decline	6	† (24)	Died (370d)
MT2-IM			Followed by 5 injections/month	117 d				Gastric Malabsorption deficiency

All animals were descendant of the GRMD couple Peter (affected) × Lady (carrier)

ISSN: 1479-5876