Figure 2From: Pathways to ischemic neuronal cell death: are sex differences relevant?The effects of the selective PARP-1 inhibitor PJ-34 in WT mice of both genders. Treatment with PJ-34 at ischemic onset reduced total infarction in male mice compared to saline treated controls (*; p < .001). A significant increase in ischemic damage was seen in PJ-34 treated females compared to control (*; p < .001) [4].Back to article page