Table 7 List of genes involving in Immune function
Pathway | Description | Gene symbol | Parametric p-value | Fold Difference (NPC/NP) |
|---|---|---|---|---|
| Â | protein kinase C, beta 1 | PRKCB1 | 2.20E-05 | 0.14 |
| Â | integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) | ITGB2 | 0.0001733 | 0.18 |
Natural killer cell mediated | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | NFATC1 | 0.0004205 | 0.23 |
cytotoxicity | phosphoinositide-3-kinase, catalytic, gamma polypeptide | PIK3CG | 0.0002216 | 0.24 |
| Â | vav 2 oncogene | VAV2 | 0.0024579 | 7.77 |
| Â | TYRO protein tyrosine kinase binding protein | TYROBP | 0.0005303 | 14.39 |
| Â | tumor necrosis factor receptor superfamily, member 10b | TNFRSF10B | 0.0006507 | 14.91 |
| Â | complement component (3d/Epstein Barr virus) receptor 2 | CR2 | 0.0001842 | 0.02 |
| Â | interleukin 1, beta | IL1B | 0.0043926 | 8.27 |
Hematopoietic cell lineage | interleukin 6 (interferon, beta 2) | IL6 | 0.0024281 | 8.29 |
| Â | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | ITGB3 | 0.0008031 | 10.39 |
| Â | CD14 antigen | CD14 | 4.15E-05 | 16.88 |
| Â | colony stimulating factor 1 (macrophage) | CSF1 | 1.00E-06 | 20.35 |
| Â | complement component (3d/Epstein Barr virus) receptor 2 | CR2 | 0.0001842 | 0.02 |
| Â | protein kinase C, beta 1 | PRKCB1 | 2.20E-05 | 0.14 |
B cell receptor | Bruton agammaglobulinemia tyrosine kinase | BTK | 5.39E-05 | 0.17 |
signaling pathway | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | NFATC1 | 0.0004205 | 0.23 |
| Â | phosphoinositide-3-kinase, catalytic, gamma polypeptide | PIK3CG | 0.0002216 | 0.24 |
| Â | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 | NFKB2 | 0.0019236 | 7.57 |
| Â | vav 2 oncogene | VAV2 | 0.0024579 | 7.77 |
| Â | glycogen synthase kinase 3 beta | GSK3B | 0.0021047 | 13.20 |
| Â | inositol polyphosphate-5-phosphatase, 145kDa | INPP5D | 4.10E-06 | 17.02 |
| Â | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | NFATC1 | 0.0004205 | 0.23 |
| Â | phosphoinositide-3-kinase, catalytic, gamma polypeptide | PIK3CG | 0.0002216 | 0.24 |
T cell receptor | cyclin-dependent kinase 4 | CDK4 | 2.20E-05 | 6.73 |
signaling pathway | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 | NFKB2 | 0.0019236 | 7.57 |
| Â | vav 2 oncogene | VAV2 | 0.0024579 | 7.77 |
| Â | mitogen-activated protein kinase kinase kinase 14 | MAP3K14 | 0.0008295 | 11.17 |
| Â | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | MS4A2 | 6.30E-06 | 0.04 |
Fc epsilon RI signaling pathway | protein kinase C, beta 1 | PRKCB1 | 2.20E-05 | 0.14 |
| Â | Bruton agammaglobulinemia tyrosine kinase | BTK | 5.39E-05 | 0.17 |
| Â | phosphoinositide-3-kinase, catalytic, gamma polypeptide | PIK3CG | 0.0002216 | 0.24 |
| Â | phospholipase A2, group V | PLA2G5 | 0.0017931 | 6.86 |
| Â | vav 2 oncogene | VAV2 | 0.0024579 | 7.77 |
| Â | inositol polyphosphate-5-phosphatase, 145kDa | INPP5D | 4.10E-06 | 17.02 |
| Â | complement component 3 | C3 | 2.25E-05 | 0.01 |
Complement and coagulation | complement component (3d/Epstein Barr virus) receptor 2 | CR2 | 0.0001842 | 0.02 |
cascades | protein S (alpha) | PROS1 | 5.00E-07 | 0.06 |
| Â | coagulation factor XIII, A1 polypeptide | F13A1 | 0.0002893 | 0.22 |
| Â | complement factor H | CFH | 0.0018395 | 0.26 |
| Â | phosphoinositide-3-kinase, catalytic, gamma polypeptide | PIK3CG | 0.0002216 | 0.24 |
Toll-like receptor signaling pathway | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 | NFKB2 | 0.0019236 | 7.57 |
| Â | interleukin 1, beta | IL1B | 0.0043926 | 8.27 |
| Â | interleukin 6 (interferon, beta 2) | IL6 | 0.0024281 | 8.29 |
| Â | CD14 antigen | CD14 | 4.15E-05 | 16.88 |