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Table 7 List of genes involving in Immune function

From: Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China

Pathway Description Gene symbol Parametric p-value Fold Difference (NPC/NP)
  protein kinase C, beta 1 PRKCB1 2.20E-05 0.14
  integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit) ITGB2 0.0001733 0.18
Natural killer cell mediated nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 NFATC1 0.0004205 0.23
cytotoxicity phosphoinositide-3-kinase, catalytic, gamma polypeptide PIK3CG 0.0002216 0.24
  vav 2 oncogene VAV2 0.0024579 7.77
  TYRO protein tyrosine kinase binding protein TYROBP 0.0005303 14.39
  tumor necrosis factor receptor superfamily, member 10b TNFRSF10B 0.0006507 14.91
  complement component (3d/Epstein Barr virus) receptor 2 CR2 0.0001842 0.02
  interleukin 1, beta IL1B 0.0043926 8.27
Hematopoietic cell lineage interleukin 6 (interferon, beta 2) IL6 0.0024281 8.29
  integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) ITGB3 0.0008031 10.39
  CD14 antigen CD14 4.15E-05 16.88
  colony stimulating factor 1 (macrophage) CSF1 1.00E-06 20.35
  complement component (3d/Epstein Barr virus) receptor 2 CR2 0.0001842 0.02
  protein kinase C, beta 1 PRKCB1 2.20E-05 0.14
B cell receptor Bruton agammaglobulinemia tyrosine kinase BTK 5.39E-05 0.17
signaling pathway nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 NFATC1 0.0004205 0.23
  phosphoinositide-3-kinase, catalytic, gamma polypeptide PIK3CG 0.0002216 0.24
  nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 NFKB2 0.0019236 7.57
  vav 2 oncogene VAV2 0.0024579 7.77
  glycogen synthase kinase 3 beta GSK3B 0.0021047 13.20
  inositol polyphosphate-5-phosphatase, 145kDa INPP5D 4.10E-06 17.02
  nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 NFATC1 0.0004205 0.23
  phosphoinositide-3-kinase, catalytic, gamma polypeptide PIK3CG 0.0002216 0.24
T cell receptor cyclin-dependent kinase 4 CDK4 2.20E-05 6.73
signaling pathway nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 NFKB2 0.0019236 7.57
  vav 2 oncogene VAV2 0.0024579 7.77
  mitogen-activated protein kinase kinase kinase 14 MAP3K14 0.0008295 11.17
  membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) MS4A2 6.30E-06 0.04
Fc epsilon RI signaling pathway protein kinase C, beta 1 PRKCB1 2.20E-05 0.14
  Bruton agammaglobulinemia tyrosine kinase BTK 5.39E-05 0.17
  phosphoinositide-3-kinase, catalytic, gamma polypeptide PIK3CG 0.0002216 0.24
  phospholipase A2, group V PLA2G5 0.0017931 6.86
  vav 2 oncogene VAV2 0.0024579 7.77
  inositol polyphosphate-5-phosphatase, 145kDa INPP5D 4.10E-06 17.02
  complement component 3 C3 2.25E-05 0.01
Complement and coagulation complement component (3d/Epstein Barr virus) receptor 2 CR2 0.0001842 0.02
cascades protein S (alpha) PROS1 5.00E-07 0.06
  coagulation factor XIII, A1 polypeptide F13A1 0.0002893 0.22
  complement factor H CFH 0.0018395 0.26
  phosphoinositide-3-kinase, catalytic, gamma polypeptide PIK3CG 0.0002216 0.24
Toll-like receptor signaling pathway nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 NFKB2 0.0019236 7.57
  interleukin 1, beta IL1B 0.0043926 8.27
  interleukin 6 (interferon, beta 2) IL6 0.0024281 8.29
  CD14 antigen CD14 4.15E-05 16.88