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Table 2 Top 70 up-regulated genes

From: Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China

No.

Gene symbol

False discovery rate

Fold difference

Description

1

SCAM-1

< 1e-07

22.68

vinexin beta (SH3-containing adaptor molecule-1)

2

SNTB1

< 1e-07

22.04

syntrophin, beta 1 (dystrophin-associated protein A1, 59 kDa, basic component 1)

3

DMWD

< 1e-07

21.75

dystrophia myotonica-containing WD repeat motif

4

NPFF

< 1e-07

20.72

neuropeptide FF-amide peptide precursor

5

FXYD3

< 1e-07

6.97

FXYD domain containing ion transport regulator 3

6

ATP6V0B

< 1e-07

5.77

ATPase, H+ transporting, lysosomal 21 kDa, V0 subunit c"

7

PPIB

< 1e-07

4.64

peptidylprolyl isomerase B (cyclophilin B)

8

HIST1H4C

< 1e-07

3.81

histone 1, H4c

9

PHB

9.40e-06

7.07

prohibitin

10

NME1

9.40e-06

5.00

non-metastatic cells 1, protein (NM23A) expressed in

11

NDUFA9

9.40e-06

3.34

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39 kDa

12

BUB1B

1.20e-05

2.77

BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)

13

GRK5

1.34e-05

21.03

G protein-coupled receptor kinase 5

14

TPI1

1.34e-05

10.82

triosephosphate isomerase 1

15

CYC1 *

1.34e-05

10.36

cytochrome c-1

16

GPC5

1.55e-05

19.28

glypican 5

17

BYSL

1.67e-05

41.59

bystin-like

18

COX5B

1.67e-05

12.52

cytochrome c oxidase subunit Vb

19

KATNB1

1.84e-05

18.37

katanin p80 (WD repeat containing) subunit B 1

20

PRKAB2

2.03e-05

14.24

protein kinase, AMP-activated, beta 2 non-catalytic subunit

21

PSMB3

2.03e-05

7.43

proteasome (prosome, macropain) subunit, beta type, 3

22

PET112L

2.16e-05

21.46

PET112-like (yeast)

23

PSMD8

2.16e-05

4.88

proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

24

CSF1

2.25e-05

20.35

colony stimulating factor 1 (macrophage)

25

SFTPA2

2.25e-05

17.66

surfactant, pulmonary-associated protein A2

26

PTCD1

2.25e-05

7.36

pentatricopeptide repeat domain 1

27

AARS

2.25e-05

6.65

alanyl-tRNA synthetase

28

GUK1

2.58e-05

5.61

guanylate kinase 1

29

RPS5

2.58e-05

4.66

ribosomal protein S5

30

MTL5

3.3e-05

14.60

metallothionein-like 5, testis-specific (tesmin)

31

MIF *

3.8e-05

10.72

macrophage migration inhibitory factor (glycosylation-inhibiting factor)

32

POLR2H

3.94e-05

4.68

polymerase (RNA) II (DNA directed) polypeptide H

33

IFITM2

4.38e-05

4.17

interferon induced transmembrane protein 2 (1–8D)

34

MUTYH

4.41e-05

19.61

mutY homolog (E. coli)

35

ITPKA

4.41e-05

15.19

inositol 1,4,5-trisphosphate 3-kinase A

36

FDPS

5.36e-05

3.45

farnesyl diphosphate synthase

37

HIST1H2BG

6.08e-05

10.23

histone 1, H2bg

38

INPP5D

6.15e-05

17.02

inositol polyphosphate-5-phosphatase, 145 kDa

39

IDH3G

6.47e-05

47.05

isocitrate dehydrogenase 3 (NAD+) gamma

40

ERF

6.49e-05

15.57

Ets2 repressor factor

41

PTPRJ

6.54e-05

13.86

protein tyrosine phosphatase, receptor type, J

42

ATP5G1

7.90e-05

4.82

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c, isoform 1

43

CDC45L

8.49e-05

22.94

CDC45 cell division cycle 45-like (S. cerevisiae)

44

ENO1

9.67e-05

4.75

enolase 1, (alpha)

45

IDH3B

0.0001064

3.81

isocitrate dehydrogenase 3 (NAD+) beta

46

ST3GAL4

0.0001140

28.99

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

47

DDR2

0.0001152

15.87

discoidin domain receptor family, member 2

48

IFI30

0.0001188

3.88

interferon, gamma-inducible protein 30

49

EIF4G1

0.0001282

3.31

eukaryotic translation initiation factor 4 gamma, 1

50

CXorf27

0.0001372

11.62

chromosome X open reading frame 27

51

EPB41

0.0001423

4.05

erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)

52

RPS15

0.0001427

6.91

ribosomal protein S15

53

ABCA3

0.0001432

30.18

ATP-binding cassette, sub-family A (ABC1), member 3

54

CGA

0.0001508

12.31

glycoprotein hormones, alpha polypeptide

55

SLC37A4

0.0001527

23.08

solute carrier family 37 (glycerol-6-phosphate transporter), member 4

56

NDUFB8

0.0001527

3.56

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19 kDa

57

CSPG4

0.0001583

60.14

chondroitin sulfate proteoglycan 4 (melanoma-associated)

58

MTHFD1

0.0001583

21.57

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1,

59

CYP3A5

0.0001586

17.90

cytochrome P450, family 3, subfamily A, polypeptide 5

60

FKBP4

0.0001611

6.51

FK506 binding protein 4, 59 kDa

61

SCO2

0.0001760

14.31

SCO cytochrome oxidase deficient homolog 2 (yeast)

62

DPM2

0.0001846

12.99

dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit

63

NRGN

0.0001945

16.26

neurogranin (protein kinase C substrate, RC3)

64

TUBA2

0.0001988

8.87

tubulin, alpha 2

65

GAPD

0.0001990

4.99

glyceraldehyde-3-phosphate dehydrogenase

66

CDK4

0.0002205

6.73

cyclin-dependent kinase 4

67

BIRC5

0.0002380

6.62

baculoviral IAP repeat-containing 5 (survivin)

68

LAMB3 *

0.0002380

5.33

laminin, beta 3

69

SSR4

0.0002380

3.81

signal sequence receptor, delta (translocon-associated protein delta)

70

PIK4CA

0.0002398

12.01

phosphatidylinositol 4-kinase, catalytic, alpha polypeptide

  1. * Genes appeared in table 4