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Table 2 Top 70 up-regulated genes

From: Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China

No. Gene symbol False discovery rate Fold difference Description
1 SCAM-1 < 1e-07 22.68 vinexin beta (SH3-containing adaptor molecule-1)
2 SNTB1 < 1e-07 22.04 syntrophin, beta 1 (dystrophin-associated protein A1, 59 kDa, basic component 1)
3 DMWD < 1e-07 21.75 dystrophia myotonica-containing WD repeat motif
4 NPFF < 1e-07 20.72 neuropeptide FF-amide peptide precursor
5 FXYD3 < 1e-07 6.97 FXYD domain containing ion transport regulator 3
6 ATP6V0B < 1e-07 5.77 ATPase, H+ transporting, lysosomal 21 kDa, V0 subunit c"
7 PPIB < 1e-07 4.64 peptidylprolyl isomerase B (cyclophilin B)
8 HIST1H4C < 1e-07 3.81 histone 1, H4c
9 PHB 9.40e-06 7.07 prohibitin
10 NME1 9.40e-06 5.00 non-metastatic cells 1, protein (NM23A) expressed in
11 NDUFA9 9.40e-06 3.34 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39 kDa
12 BUB1B 1.20e-05 2.77 BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)
13 GRK5 1.34e-05 21.03 G protein-coupled receptor kinase 5
14 TPI1 1.34e-05 10.82 triosephosphate isomerase 1
15 CYC1 * 1.34e-05 10.36 cytochrome c-1
16 GPC5 1.55e-05 19.28 glypican 5
17 BYSL 1.67e-05 41.59 bystin-like
18 COX5B 1.67e-05 12.52 cytochrome c oxidase subunit Vb
19 KATNB1 1.84e-05 18.37 katanin p80 (WD repeat containing) subunit B 1
20 PRKAB2 2.03e-05 14.24 protein kinase, AMP-activated, beta 2 non-catalytic subunit
21 PSMB3 2.03e-05 7.43 proteasome (prosome, macropain) subunit, beta type, 3
22 PET112L 2.16e-05 21.46 PET112-like (yeast)
23 PSMD8 2.16e-05 4.88 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
24 CSF1 2.25e-05 20.35 colony stimulating factor 1 (macrophage)
25 SFTPA2 2.25e-05 17.66 surfactant, pulmonary-associated protein A2
26 PTCD1 2.25e-05 7.36 pentatricopeptide repeat domain 1
27 AARS 2.25e-05 6.65 alanyl-tRNA synthetase
28 GUK1 2.58e-05 5.61 guanylate kinase 1
29 RPS5 2.58e-05 4.66 ribosomal protein S5
30 MTL5 3.3e-05 14.60 metallothionein-like 5, testis-specific (tesmin)
31 MIF * 3.8e-05 10.72 macrophage migration inhibitory factor (glycosylation-inhibiting factor)
32 POLR2H 3.94e-05 4.68 polymerase (RNA) II (DNA directed) polypeptide H
33 IFITM2 4.38e-05 4.17 interferon induced transmembrane protein 2 (1–8D)
34 MUTYH 4.41e-05 19.61 mutY homolog (E. coli)
35 ITPKA 4.41e-05 15.19 inositol 1,4,5-trisphosphate 3-kinase A
36 FDPS 5.36e-05 3.45 farnesyl diphosphate synthase
37 HIST1H2BG 6.08e-05 10.23 histone 1, H2bg
38 INPP5D 6.15e-05 17.02 inositol polyphosphate-5-phosphatase, 145 kDa
39 IDH3G 6.47e-05 47.05 isocitrate dehydrogenase 3 (NAD+) gamma
40 ERF 6.49e-05 15.57 Ets2 repressor factor
41 PTPRJ 6.54e-05 13.86 protein tyrosine phosphatase, receptor type, J
42 ATP5G1 7.90e-05 4.82 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c, isoform 1
43 CDC45L 8.49e-05 22.94 CDC45 cell division cycle 45-like (S. cerevisiae)
44 ENO1 9.67e-05 4.75 enolase 1, (alpha)
45 IDH3B 0.0001064 3.81 isocitrate dehydrogenase 3 (NAD+) beta
46 ST3GAL4 0.0001140 28.99 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
47 DDR2 0.0001152 15.87 discoidin domain receptor family, member 2
48 IFI30 0.0001188 3.88 interferon, gamma-inducible protein 30
49 EIF4G1 0.0001282 3.31 eukaryotic translation initiation factor 4 gamma, 1
50 CXorf27 0.0001372 11.62 chromosome X open reading frame 27
51 EPB41 0.0001423 4.05 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
52 RPS15 0.0001427 6.91 ribosomal protein S15
53 ABCA3 0.0001432 30.18 ATP-binding cassette, sub-family A (ABC1), member 3
54 CGA 0.0001508 12.31 glycoprotein hormones, alpha polypeptide
55 SLC37A4 0.0001527 23.08 solute carrier family 37 (glycerol-6-phosphate transporter), member 4
56 NDUFB8 0.0001527 3.56 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19 kDa
57 CSPG4 0.0001583 60.14 chondroitin sulfate proteoglycan 4 (melanoma-associated)
58 MTHFD1 0.0001583 21.57 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1,
59 CYP3A5 0.0001586 17.90 cytochrome P450, family 3, subfamily A, polypeptide 5
60 FKBP4 0.0001611 6.51 FK506 binding protein 4, 59 kDa
61 SCO2 0.0001760 14.31 SCO cytochrome oxidase deficient homolog 2 (yeast)
62 DPM2 0.0001846 12.99 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
63 NRGN 0.0001945 16.26 neurogranin (protein kinase C substrate, RC3)
64 TUBA2 0.0001988 8.87 tubulin, alpha 2
65 GAPD 0.0001990 4.99 glyceraldehyde-3-phosphate dehydrogenase
66 CDK4 0.0002205 6.73 cyclin-dependent kinase 4
67 BIRC5 0.0002380 6.62 baculoviral IAP repeat-containing 5 (survivin)
68 LAMB3 * 0.0002380 5.33 laminin, beta 3
69 SSR4 0.0002380 3.81 signal sequence receptor, delta (translocon-associated protein delta)
70 PIK4CA 0.0002398 12.01 phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
  1. * Genes appeared in table 4