Figure 7
From: Correlation between NK function and response to trastuzumab in metastatic breast cancer patients
Time to tumor progression is not correlated with the ADCC activity. A cut-off of 10%, 6% and 4% cytotoxicity was arbitrarly chosen to discriminate between high and low levels ADCC at the three E:T ratios of 50:1, 25:1 and 12:1 respectively and a stratified PFS curve was created from these values. The pattern of the two curves and the Log-Rank test p values demonstrated that time to tumor progression was not correlated with the ADCC.