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Table 2 WNT pathway genes upregulated 4-fold or more in AF-set B compared to AF-set A

From: Identification of heterogeneity among soft tissue sarcomas by gene expression profiles from different tumors

Gene Symbol

Gene Name

Fragment Name

Fold change-up in AF-set B

CCND2

cyclin D2

200953_s_at

7

CSNK1A1

casein kinase 1, alpha 1

208865_at

4.9

CSNK2B

casein kinase 2, beta polypeptide

201390_s_at

4.4

CTBP1

C-terminal binding protein 1

203392_s_at

7.8

CTBP2, LOC440008

C-terminal binding protein 2, LOC440008

210835_s_at

5.8

DVL3

dishevelled, dsh homolog 3 (Drosophila)

201908_at

6.4

FZD1

frizzled homolog 1 (Drosophila)

204451_at

4.8

JUN

v-jun sarcoma virus 17 oncogene homolog (avian)

201464_x_at

5.1

PPP2CB

protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform

201375_s_at

5.4

PPP3CB

protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)

202432_at

6.7

PRKACB

protein kinase, cAMP-dependent, catalytic, beta

202741_at

7.1

RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

208640_at

5.4

RHOA

ras homolog gene family, member A

200059_s_at

5.6

RHOB

ras homolog gene family, member B

212099_at

8.2

SFRP2

secreted frizzled-related protein 2

223121_s_at

4.9

SFRP4

secreted frizzled-related protein 4

204051_s_at

5.6

SKP1A

S-phase kinase-associated protein 1A (p19A)

200718_s_at

5.9

TBL1XR1

transducin (beta)-like 1X-linked receptor 1

223013_at

4.8

WNT5A

wingless-type MMTV integration site family, member 5A

205990_s_at

6.9

  1. Fold change analysis was performed using genes involved in the wnt-signaling pathway. Genes that were most differentially expressed between AF-set A and AF-set B are listed.