Differential susceptibility of C57BL/6NCr and B6.Cg-Ptprca mice to commensal bacteria after whole body irradiation in translational bone marrow transplant studies

Table 2 Improved survival of B6.Cg-Ptprc^a/NCr mice to radiation doses of 1000 and 1100 cGy.

Inoculum type	Recip	Symptoms	#affected	% affected	Rads (cGy)	Irradiator
BM	B6 (Ly5.2)	None	0/10	0	1000 (single)	X-ray
BM	B6 (Ly5.2)	None	0/10	0	1000 (single)	X-ray
BM	B6 (Ly5.2)	None	0/10	0	1000 (single)	X-ray
BM+Tc	B6 (Ly5.2)	None	0/5	0	1100 (single)	gamma
BM+Tc	B6 (Ly5.2)	none	0/9	0	1100 (single)	gamma
BM+Tc	B6 (Ly5.2)	None	0/27	0	1100 (split)	gamma
BM +Tc	B6 (Ly5.2)	None	0/30	0	1100 (split)	gamma
BM+Tc	B6 (Ly5.2)	None	0/25	0	1100 (split)	gamma
BM+ Tc	B6 (Ly5.2)	Yes	7/24	29%	1100 single	gamma

B6.Cg-Ptprc^a/NCr (B6LY5.2/Cr), referred as Ly5.2 congenics, receiving similar radiation doses as shown in Table 1. Recipients were reconstituted in these experiments with either bone marrow (BM) alone or BM and T-cells (Tc).

ISSN: 1479-5876