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Table 1 C57BL/6NCr are sensitive to irradiation doses >1000 cGy.

From: Differential susceptibility of C57BL/6NCr and B6.Cg-Ptprca mice to commensal bacteria after whole body irradiation in translational bone marrow transplant studies

Inoculum type Recipients First day Symptoms observed post BMT #affected % affected Treatment Rads (cGy) Irradiator
BM+ Tc B6 (Ly5.1) 6 2/4 50   1300 split Xray
BM + splenocytes B6 (Ly5.1) 7 2/4 50   1100 single Xray
BM + Tc B6 (Ly5.1) 9 2/4 50   1100 single Xray
BM+Tc B6 (Ly5.1) 7 1/3 33 EL-4 1100 single Xray
BM+Tc B6 (Ly5.1) 7 3/12 25 EL-4 1100 single Xray
BM+T c B6 (Ly5.1) 6 2/6 33 EL-4 1100 single Xray
BM+Tc B6 (Ly5.1) 6 8/8 100 EL-4 1100 single Xray
BM+Tc B6 (Ly5.1) 6 11/20 55   1100 single gamma
BM+Tc B6 (Ly5.1) 6 2/4 50   1100 single gamma
BM+Tc B6 (Ly5.1) 6 4/5 80   1100 split gamma
BM+Tc B6 (Ly5.1) 5 4/6 66   1300 split gamma
BM+Tc B6 (Ly5.1) 5 9/11 81 MBL-2 1300 split gamma
BM+DC B6 (Ly5.1) 4 5/5 100 DC 1100 single X-ray
BM+Tc B6 (Ly5.1) 5 5/5 100   1100 single gamma
BM+Tc B6 (Ly5.1) 5 3/9 33   1000 single gamma
  1. C57BL/6NCr underwent BMT and exhibited unexpected deaths. Animals were reconstituted with bone marrow (BM) and T-cells (Tc), or bulk splenocytes (splenocytes) or dendritic cells (DC). Symptoms started as early as day +4 post-transplantation. Some animals received MBL-2 or EL-4 leukemia cells. Ionizing radiation was given in a single or fractionated (split) dose or administered with an X-ray diffraction instrument. Split regimens were delivered in two equal amounts separated at least 3 hours apart.