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Table 5 Univariate Analysis of Cox Proportional Hazards Model for Overall Survival in NPC patients

From: Elevated expressions of survivin and VEGF protein are strong independent predictors of survival in advanced nasopharyngeal carcinoma

Characteristics Hazard ratio 95%CI P
Age (years, <46 vs. ≥ 46) 1.558 1.044–2.326 0.030
Sex (male vs. female) 0.447 0.264–0.754 0.003
T-stage (T1~2 vs. T3~4) 1.386 0.914–2.101 0.124
N-stage (N0 vs. N1~3) 0.978 0.628–1.524 0.923
Clinical stage (I/II vs. III/IV) 1.817 1.091–3.025 0.022
Recurrence (no vs. yes) 1.560 1.018–2.391 0.041
Metastasis (no vs. yes) 2.023 1.177–3.478 0.011
VEGF (low expression vs. over-expression) 2.112 1.277–3.495 0.004
Survivin (low expression vs. over-expression) 2.132 1.301–3.494 0.003