% Annexin V levels (mean ± SD)
|
CD4 (cells/mm3)
|
CD8(cells/mm3)
|
CD4:CD8 Ratio
|
---|
|
Baseline
|
6 YR
|
P-value
|
Baseline
|
6 YR
|
P-value
|
Baseline
|
6 YR
|
P-value
|
---|
Low 2.2 ± 2.1
|
625 ± 221
|
1209 ± 164
|
0.001
|
967 ± 386
|
915 ± 308
|
0.766
|
0.76 ± 0.4
|
1.55 ± 0.9
|
0.038
|
High 17.0 ± 6.0
|
527 ± 132
|
754 ± 320
|
0.098
|
1234 ± 660
|
1172 ± 456
|
0.728
|
0.56 ± 0.36
|
0.7 ± 0.34
|
0.215
|
- A repeated measures ANOVA showed a significant difference in the low annexin group for CD4 values from baseline to year 6 with a p value of p ≥ 0.001. The high annexin group CD4 values were not significant from baseline to year 6 with a p value of ≥ 0.098. CD8 values in both the low and high apoptosis groups were not significant for the baseline or 6 year analysis. The CD4:CD8 ratio for the low apoptosis group was significant with a p value of ≥ 0.038, but the ratio for the high apoptosis group was not significant (p ≥ 0.215) after 6 years.