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Table 1 Increase in CD4 Cell Counts and CD4:CD8 Ratio After 3 scIL-3 Cycles.

From: CD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV

scIL-2 Dosage Change in CD4 Number Increase in Ratio*
7.5 MIU(n = 4) 863 ± 434 0.88 ± 0.15
1.5 MIU(n = 5) 554 ± 458 0.53 ± 0.09
Control (n = 3) 442 ± 284 0.23 ± 0.14
  1. * Day 65 in treated and week 24 in controls.
  2. All different from each other (p = < 0.01). All patients increased their CD4:CD8 ratio, with the high dose IL-2 patients responding best. There is one missing endpoint in the high dosage at Day 65 and one in the group that received no IL-2 at 24 weeks.