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Table 1 Cytokine levels (pg/ml) pre and post-rhIL-12 infusion

From: Phase II study of intraperitoneal recombinant interleukin-12 (rhIL-12) in patients with peritoneal carcinomatosis (residual disease < 1 cm) associated with ovarian cancer or primary peritoneal carcinoma

Accession Number Sampling Timepoint Sample ID Results (pg/ml)
    TNF-α IL-12 p70 INF-γ VEGF IL-10 IL-8 IP-10
5 Baseline 1 15.3 6.7 < 0.78 < 2.30 5.9 38.6 7.6
  6 Hr 2 16.1 4973.2 1.9 56.4 18.8 270.0 191.6
  24 Hr 3 15.7 4722.9 38.1 33.8 35.2 72.7 263.8
  48 Hr 4 18.7 8004.8 215.9 74.1 80.5 213.1 303.8
  Baseline 5 105.4 7.6 1.0 36.4 36.5 190.0 12.9
  6 Hr 6 34.6 11040.0 140.1 348.8 3686.9 1254.7 460.2
  24 Hr 28 70.1 3789.5 232.5 238.8 553.0 3897.2 367.2
  48 Hr 7 43.4 1085.4 198.9 178.8 187.1 6363.6 354.0
11 Baseline 8 16.1 7.1 < 0.78 48.4 18.4 67.7 7.9
  6 Hr 9 17.4 5380.8 < 0.78 69.7 39.9 122.8 251.2
  24 Hr 10 74.1 5217.5 56.8 87.3 72.2 876.7 354.3
  48 Hr 11 48.0 934.2 220.0 82.6 30.1 128.0 1153.9
10 Baseline 12 16.6 6.1 1.0 89.5 5.5 231.7 7.9
  6 Hr 13 55.2 25700.0 37.7 447.5 296.5 1577.8 351.3
  24 Hr 14 185.3 6580.7 236.3 428.0 90.7 1538.3 429.6
  48 Hr 15 56.0 561.2 155.3 379.3 27.3 2923.8 355.6
4 Baseline 20 15.3 6.4 < 0.78 < 2.30 3.6 7.2 < 0.95
  6 Hr 21 16.1 5937.5 2.2 82.8 4.8 251.3 238.2
  24 Hr 22 17.4 5547.5 74.8 69.4 9.7 93.2 258.2
  48 Hr 23 35.1 4283.1 504.3 55.7 27.3 124.7 275.7
3 Baseline 24 17.4 8.7 10.0 110.3 10.4 492.4 9.0
  6 Hr 25 17.4 10214.7 19.5 213.7 15.8 1711.3 229.7
  24 Hr 26 40.6 4103.6 184.2 187.9 19.9 3348.5 223.9
  48 Hr 27 16.6 30.7 108.8 37.7 3.6 475.5 202.0