Figure 5
In vitro angiogenesis assays. Primary endothelial cells isolated from mouse lung were induced to form tubes in a three-dimensional fibrin matrix under the influence of growth factors, in the presence of 339.1 or control IgG, (A). Results from triplicate wells were quantified using the Discovery-1 system (B). Inclusion of 339.1 in this assay results in a decrease in tube formation.