Figure 6From: The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitizationEffect of Phenoxodiol on YUMAC (A) and YUSAC2 (B) cells. Cells were treated with a single dose of Phenoxodiol (10 μg/mL) for varying time points (0, 4, 8, and 24 hours). XIAP and caspase-2 expression were determined by western blot analysis. Caspase-3, -8, and -9 activities were determined by the Caspase-Glo 3, 8, and 9 assays, respectively.Back to article page