Figure 5From: Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell linesProtein expression of apoptotic markers. (A) p53 and NAG-1 protein expression in LoVo cells after different exposure times to NCX 4040. (B) NAG-1 protein expression in LRWZ cells after different exposure times to NCX 4040. (C) Cytochrome c, caspase-9 and -3 protein expression in LoVo cells: lane a, untreated; lane b, 6-hour NCX 4040 exposure (10 μM). (D) Cytochrome c, caspase-9 and -3 protein expression in LRWZ cells: lane a, untreated; lane b, 14-hour NCX 4040 exposure (50 μM).Back to article page