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Table 2 Results of the univariate analysis testing the panel of cytokines and CRP

From: Basal cytokines profile in metastatic renal cell carcinoma patients treated with subcutaneous IL-2-based therapy compared with that of healthy donors

Parameters

% Pts

Median Survival (CI) (mos)

p Value (log rank)

IL-Iβ:

   

   < 27,8 pg/ml

57

11 (5.05–16.95)

0.1761

   > 27,8 pg/ml

43

24 (14.20–33.80)

 

IL-6:

   

   < 4 pg/ml

40

25 (11.82–38.18)

0.0295

   > 4 pg/ml

60

9 (5.44–12.56)

 

IL-8:

   

   < 50,7 pg/ml

62

17 (0.00–34.06)

0.0370

   > 50,7 pg/ml

38

9 (0.00–23.16)

 

IL-10:

   

   < 0 pg/ml

19

19 (1.82–36.18)

0.3954

   > 0 pg/ml

81

15 (7.04–22.96)

 

IL-12:

   

   < 5,2 pg/ml

64

15 (6.93–23.07)

0.0882

   > 5,2 pg/ml

36

25 (19.87–30.13)

 

TNF-α:

   

   < 0 pg/ml

19

7 (0.80–13.20)

0.1159

   > 0 pg/ml

81

20 (10.56–29.44)

 

CRP:

   

   < 0,8 mg/dl

46

31 (21.29–40.71)

< 0.0001

   > 0,8 mg/dl

54

8 (5.68–10.32)

 
  1. Abbreviations: CRP, C-reactive protein; IL, interleukin; TNF, tumor necrosis factor