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Figure 2 | Journal of Translational Medicine

Figure 2

From: Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells

Figure 2

Induction of alloresponses by MR-targeted vaccine combined with TLR activation. DCs from normal donor PBMCs were untreated (2a, 2c) or treated (2b, 2c) with vaccine (B11-hCGβ at 10 μg/ml) in combination with TLR activating ligands and added to allogeneic T cells post incubation at different DC: T cell ratios. T cells were pulsed with [3H]-TdR on day 4 and harvested on day 5 to assess incorporation of DNA-associated radioactivity. Experiments were performed in triplicates. Data are shown as mean ± S.D. of 2 donor (2a, 2b) and 3 donor samples (2c), respectively.

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