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Table 2 Charles River Laboratories study

From: Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles

A_id C.Dose.Day H_score B_class A_id C.Dose.Day H_score B_class
1 All.006.03 0 -1 65 Pur.075.03 0 -1
2 All.006.03 0 -1 66 Pur.075.03 0 -1
3 All.006.03 0 -1 67 Pur.075.03 0 -1
4 All.006.03 0 -1 68 Pur.075.03 0 -1
5 All.030.03 0 -1 69 Pur.075.07 3 1
6 All.030.03 0 -1 70 Pur.075.07 2 1
7 All.030.03 0 -1 71 Pur.075.07 0 -1
8 All.030.03 0 -1 72 Pur.075.07 0 -1
9 All.100.03 2 1 73 Tob.006.03 0 -1
10 All.100.03 2 1 74 Tob.006.03 0 -1
11 All.100.03 2 1 75 Tob.006.03 0 -1
12 All.100.03 2 1 76 Tob.006.03 0 -1
13 All.100.03 1 1 77 Tob.030.14 1 1
14 All.100.03 1 1 78 Tob.030.14 0 -1
15 All.100.03 1 1 79 Tob.030.14 0 -1
16 All.100.03 1 1 80 Tob.030.14 0 -1
17 All.100.07 2 1 81 Tob.060.03 0 -1
18 All.100.07 2 1 82 Tob.060.03 0 -1
19 All.100.07 1 1 83 Tob.060.03 0 -1
20 All.100.07 1 1 84 Tob.060.03 0 -1
21 All.100.14 2 1 85 Tob.060.14 2 1
22 All.100.14 2 1 86 Tob.060.14 2 1
23 All.100.14 2 1 87 Tob.060.14 2 1
24 All.100.14 1 1 88 Tob.060.14 2 1
25 D-S.750.03 4 1 89 Veh.000.03 1 1
26 D-S.750.03 4 1 90 Veh.000.03 0 -1
27 D-S.750.03 4 1 91 Veh.000.03 0 -1
28 D-S.750.03 0 -1 92 Veh.000.03 0 -1
29 D-S.750.14 2 1 93 Veh.000.03 0 -1
30 D-S.750.14 2 1 94 Veh.000.03 0 -1
31 D-S.750.14 2 1 95 Veh.000.03 0 -1
32 HCB.007.5.03 0 -1 96 Veh.000.03 0 -1
33 HCB.007.5.03 0 -1 97 Veh.000.03 0 -1
34 HCB.007.5.03 0 -1 98 Veh.000.03 0 -1
35 HCB.040.03 1 1 99 Veh.000.03 0 -1
36 HCB.040.03 0 -1 100 Veh.000.03 0 -1
37 HCB.040.03 0 -1 101 Veh.000.03 0 -1
38 HCB.040.14 2 1 102 Veh.000.03 0 -1
39 HCB.040.14 2 1 103 Veh.000.03 0 -1
40 HCB.040.14 2 1 104 Veh.000.03 0 -1
41 HCB.040.14 2 1 105 Veh.000.03 0 -1
42 HCB.100.03 4 1 106 Veh.000.03 0 -1
43 HCB.100.03 4 1 107 Veh.000.03 0 -1
44 HCB.100.03 3 1 108 Veh.000.03 0 -1
45 HCB.100.03 3 1 109 Veh.000.07 1 1
46 Pur.005.03 0 -1 110 Veh.000.07 0 -1
47 Pur.005.03 0 -1 111 Veh.000.07 0 -1
48 Pur.005.03 0 -1 112 Veh.000.07 0 -1
49 Pur.005.03 0 -1 113 Veh.000.07 0 -1
50 Pur.020.03 2 1 114 Veh.000.07 0 -1
51 Pur.020.03 0 -1 115 Veh.000.07 0 -1
52 Pur.020.03 0 -1 116 Veh.000.07 0 -1
53 Pur.020.03 0 -1 117 Veh.000.14 1 1
54 Pur.020.03 0 -1 118 Veh.000.14 1 1
55 Pur.020.03 0 -1 119 Veh.000.14 0 -1
56 Pur.020.03 0 -1 120 Veh.000.14 0 -1
57 Pur.020.03 0 -1 121 Veh.000.14 0 -1
58 Pur.020.07 0 -1 122 Veh.000.14 0 -1
59 Pur.020.07 0 -1 123 Veh.000.14 0 -1
60 Pur.020.07 0 -1 124 Veh.000.14 0 -1
61 Pur.020.14 3 1 125 Veh.000.14 0 -1
62 Pur.020.14 3 1 126 Veh.000.14 0 -1
63 Pur.020.14 3 1 127 Veh.000.14 0 -1
64 Pur.020.14 2 1 128 Veh.000.14 0 -1
  1. Charles River Laboratories samples with histopathological grade and binary class label for SVM classification. The columns are: A_id, the animal identification number; C.Dose.Day, Compound.Dose.Day; H_score, histopathology grade; B_class, the designated SVM class label for binary classification training or testing. The compounds are: All (Allopurinol), D-s (D-serine), HCB (Hexachloro 1,3, butadiene), Pur (Puromycin), Tob (Tobramycin) and Veh (Vehicle control). The designated SVM binary class label was assigned based on the pathology grade. 1–5 labeled as 1, the positive class and 0 labeled as -1, the negative class.