Skip to main content
Figure 1 | Journal of Translational Medicine

Figure 1

From: Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles

Figure 1

Heatmap to illustrate the kidney proximal tuble toxicity classification by SVM. Top ranked 100 up regulated genes (positive weighted) and 25 down regulated genes (down regulated) by linear SVM were used to correlate with the kidney proximal tubule toxicity and SVM predicted class label. The first column is PT histopathology grade. The second column is the SVM predicted class label: -1 is predicted non toxic and 1 is predicted toxic. After a Blank column for separation, the rest columns are the selected top ranked genes in logratios. The rows in the heatmap represent samples.

Back to article page