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Table 1 Genes involved in NK cell function with significantly higher expression in IFN-DC in comparison to IL-4/TNF-DC (q-value <5%)

From: Monocyte derived dendritic cells generated by IFN-α acquire mature dendritic and natural killer cell properties as shown by gene expression analysis

Gene Symbol Gene Symbol Fold change
IL7R interleukin 7 receptor 8.66
TRAIL tumor necrosis factor (ligand) superfamily, member 10 5.02
DEFA1 defensin, alpha 1, myeloid-related sequence 4.64
GZMB granzyme B (cytotoxic T-lymphocyte-associated serine esterase 1) 3.33
GZMM granzyme M (lymphocyte met-ase 1) 2.09
KLRF1 killer cell lectin-like receptor subfamily F, member 1 1.91
LAG3 lymphocyte-activation gene 3 1.88
LTB lymphotoxin beta (TNF superfamily, member 3) 1.83
GZMA granzyme A (cytotoxic T-lymphocyte-associated serine esterase 3) 1.83
NKG7 natural killer cell group 7 sequence 1.77
CD2 CD2 antigen (p50), sheep red blood cell receptor 1.64
NCR2 natural cytotoxicity triggering receptor 2 1.55
IL2RB interleukin 2 receptor, beta 1.53
IL12RB2 interleukin 12 receptor, beta 2 1.48
KLRC3 killer cell lectin-like receptor subfamily C, member 3 1.45
NCR1 natural cytotoxicity triggering receptor 1 1.45
NK1 CD160 antigen 1.42
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 1.41
KLRA1 killer cell lectin-like receptor subfamily A, member 1 1.34
IL12RB1 interleukin 12 receptor, beta 1 1.33
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 1.33
CD96 CD96 antigen 1.33
FasL tumor necrosis factor (ligand) superfamily, member 6 1.32
CD49b integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.30
CXCR3 chemokine (C-X-C motif) receptor 3 1.27
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 1.27
CD56 neural cell adhesion molecule 1 1.27
KLRK1 killer cell lectin-like receptor subfamily K, member 1 1.27
IFNG interferon, gamma 1.21
IL15RA interleukin 15 receptor, alpha 1.21
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 1.19
KLRG1 killer cell lectin-like receptor subfamily G, member 1 1.19