Table 1 Genes involved in NK cell function with significantly higher expression in IFN-DC in comparison to IL-4/TNF-DC (q-value <5%)
Gene Symbol | Gene Symbol | Fold change |
|---|---|---|
IL7R | interleukin 7 receptor | 8.66 |
TRAIL | tumor necrosis factor (ligand) superfamily, member 10 | 5.02 |
DEFA1 | defensin, alpha 1, myeloid-related sequence | 4.64 |
GZMB | granzyme B (cytotoxic T-lymphocyte-associated serine esterase 1) | 3.33 |
GZMM | granzyme M (lymphocyte met-ase 1) | 2.09 |
KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | 1.91 |
LAG3 | lymphocyte-activation gene 3 | 1.88 |
LTB | lymphotoxin beta (TNF superfamily, member 3) | 1.83 |
GZMA | granzyme A (cytotoxic T-lymphocyte-associated serine esterase 3) | 1.83 |
NKG7 | natural killer cell group 7 sequence | 1.77 |
CD2 | CD2 antigen (p50), sheep red blood cell receptor | 1.64 |
NCR2 | natural cytotoxicity triggering receptor 2 | 1.55 |
IL2RB | interleukin 2 receptor, beta | 1.53 |
IL12RB2 | interleukin 12 receptor, beta 2 | 1.48 |
KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | 1.45 |
NCR1 | natural cytotoxicity triggering receptor 1 | 1.45 |
NK1 | CD160 antigen | 1.42 |
KIR3DL2 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 | 1.41 |
KLRA1 | killer cell lectin-like receptor subfamily A, member 1 | 1.34 |
IL12RB1 | interleukin 12 receptor, beta 1 | 1.33 |
KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 | 1.33 |
CD96 | CD96 antigen | 1.33 |
FasL | tumor necrosis factor (ligand) superfamily, member 6 | 1.32 |
CD49b | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 1.30 |
CXCR3 | chemokine (C-X-C motif) receptor 3 | 1.27 |
KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 | 1.27 |
CD56 | neural cell adhesion molecule 1 | 1.27 |
KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 1.27 |
IFNG | interferon, gamma | 1.21 |
IL15RA | interleukin 15 receptor, alpha | 1.21 |
KIR2DS3 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 | 1.19 |
KLRG1 | killer cell lectin-like receptor subfamily G, member 1 | 1.19 |