DC-SIGN [4.0] (CD209a) | A cell surface C-type lectin expressed by dendritic cells that mediates antigen capture for processing and presentation |
CD28 [1.6] | T cell-specific receptor for CD80 and CD86 |
CD83 [1.9] | The most reliable activation marker for mature dendritic cells |
FAS [2.1] | The apoptosis-mediating membrane-associated polypeptide that belongs to the tumor necrosis factor receptor superfamily |
Flt3L [1.7] | A ligand that expands type-1 dendritic cells and enhances the immune response by augmenting T-cell activity |
H2-DMa [2.0] | Involved in antigen processing and presentation of exogenous peptide antigens via MHC class II |
ICOSL [2.6] (B7-H2) | Is a ligand for T cell-specific, cell surface receptor ICOS and acts as a co-stimulatory signal for T-cell proliferation and cytokine secretion |
CD11c [1.7] (ITGAX) | Expressed by dendritic cells that tend to generate Th1 effectors |
LTA [1.7] (TNF-β) | Lymphotoxin α or tumor necrosis factor β |
NFKB [1.5] | A transcription factor required for STAT-4 expression during dendritic cell maturation |
XCL1 [2.5] (ATAC) | An activation-induced, T cell-derived and chemokine-related type 1 cytokine, that cooperates with interferon (IFN)-γ in the up-regulation of CD40 and interleukin (IL)-12 expression |