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Figure 4 | Journal of Translational Medicine

Figure 4

From: Semi-allogeneic vaccine for T-cell lymphoma

Figure 4

Anti-tumor protection conferred by injection of irradiated semi-allogeneic vaccines compared to co-injection of irradiated EL-4 cells plus irradiated RAG cells. The bar graph shows the average tumor weight per mouse and the standard deviation for each group of mice. The five groups were immunized as follows: 1) mock-vaccination (PBS); 2) 1 × 106 irradiated EL-4 cells (iEL-4); 3) 1 × 106 irradiated RAG cells (iRAG); 4) 1 × 106 irradiated EL-4 cells co-injected with 1 × 106 irradiated RAG cells (iEL-4 + iRAG); 5) 1 × 106 irradiated EL-4 × RAG semi-allogeneic somatic cell hybrids (iEL-4 × RAG). Using mock-vaccination (PBS) as a control, the p-values were as follows: iEL-4 p-value = 0.5469; iRAG p-value = 0.3065; iEL-4 + iRAG (co-injection) p-value = 0.0417; and iEL-4 × RAG (hybrids) p-value < 0.00001.

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