Figure 4
The anti-tumor effect of anti-LT391-06 CTLs against two HLA matched allogeneic tumor cells is antigen specific. SCID mice in control groups (●) received a s.c. injection of 5 × 105 tumor cells alone and mice in the treated groups (○) received a co-injection of 1 × 106 anti-LT391-06 CTLs s.c. A. Mice bearing A549 tumors, an allogeneic bronchioalveolar carcinoma cell line which does not express the LT391-06 Ag recognized by the tumor specific CTLs; B. Mice bearing 936T, an allogeneic tumor cell line derived from a squamous lung carcinoma which does express this antigen. (n = 5 mice/group)