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Table 2 Characteristics associated with changes in CD39 function

From: CD39 activity correlates with stage and inhibits platelet reactivity in chronic lymphocytic leukemia

 

Characteristics

Activity (pmol/min/50 K cells)

Stage

0–2

88.2*

 

3–4

44.7

History of chemotherapy?

Yes

55.8

 

No

83**

Age

< = 70 y/o

46.5*

 

> 70 y/o

92

Hemoglobin

< 13 g/dl

57.9†

 

> = 13 g/dl

89.4

  1. Statistically significant differences in CD39 activity. Stage, age, and hemoglobin levels were associated with statistically significant differences in the enzymatic activity of CD39 in patients with CLL. A history of chemotherapy was associated with a marginally significant trend towards decreased CD39 activity in CLL. Leukocyte and platelet count, gender, and length of time since diagnosis were not associated with differences in CD39 activity.
  2. *p = 0.002
  3. **p = 0.08
  4. †p = 0.03