Figure 3
From: CD39 activity correlates with stage and inhibits platelet reactivity in chronic lymphocytic leukemia
Typical FACS of normal and malignant B-lymphocytes. A. Normal B-lymphocytes B. Malignant B-lymphocytes. The majority (> 90%) of both normal and malignant B-lymphocytes are positive for CD39 and the mean expression per cell is similar. However, the number of B-lymphocytes as a percentage of the total lymphocyte gate is higher. Expression of CD39, as measured by FACS, was not clearly greater in earlier stage CLL as opposed to normal B-lymphocytes or later stage CLL, although activity was greater in earlier stage disease.